abstract：PURPOSE:To assess the status of choriocapillaris in eyes with macular atrophy secondary to age-related macular degeneration (AMD) (geographic atrophy [GA]) and Stargardt disease (STGD) using optical coherence tomography angiography (OCTA). DESIGN:Prospective, observational case series. PARTICIPANTS:A total of 14 pati...

journal_title：Ophthalmology

authors： Pellegrini M,Acquistapace A,Oldani M,Cereda MG,Giani A,Cozzi M,Staurenghi G

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:The objective of the study was to evaluate the accuracy of the Notal OCT Analyzer (NOA) versus that of a retina specialist (RS) in the automated detection of fluid on optical coherence tomography (OCT). DESIGN:A study of the performance of the NOA compared with the results from 3 RSs. PARTICIPANTS:A selection...

journal_title：Ophthalmology

authors： Chakravarthy U,Goldenberg D,Young G,Havilio M,Rafaeli O,Benyamini G,Loewenstein A

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To evaluate the effect of systemic factors on best-corrected visual acuity (BCVA) achieved with ranibizumab (Lucentis; Genentech, Inc, South San Francisco, CA) for treatment of diabetic macular edema (DME) in the RIDE and RISE phase 3 studies. DESIGN:Exploratory, post hoc analysis of 2 randomized, double-maske...

journal_title：Ophthalmology

authors： Singh RP,Habbu K,Ehlers JP,Lansang MC,Hill L,Stoilov I

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:To provide an initial assessment of the safety of a recombinant adeno-associated virus vector expressing RPE65 (rAAV2-CB-hRPE65) in adults and children with retinal degeneration caused by RPE65 mutations. DESIGN:Nonrandomized, multicenter clinical trial. PARTICIPANTS:Eight adults and 4 children, 6 to 39 years...

journal_title：Ophthalmology

authors： Weleber RG,Pennesi ME,Wilson DJ,Kaushal S,Erker LR,Jensen L,McBride MT,Flotte TR,Humphries M,Calcedo R,Hauswirth WW,Chulay JD,Stout JT

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:To report the incidence of acute postoperative endophthalmitis (POE) after cataract surgery from 2005 to 2014 in France. DESIGN:Cohort study. PARTICIPANTS:Patients undergoing operation for cataract surgery by phacoemulsification and presenting acute POE. METHODS:We identified acute POE occurring within 6 wee...

journal_title：Ophthalmology

authors： Creuzot-Garcher C,Benzenine E,Mariet AS,de Lazzer A,Chiquet C,Bron AM,Quantin C

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:To describe the clinical presentation and outcomes of Acanthamoeba keratitis (AK) in rigid gas permeable (RGP) contact lens wearers and to identify modifiable risk factors. DESIGN:Case-control investigation. PARTICIPANTS:Patients were RGP contact lens-wearing United States residents with a diagnosis of AK fro...

journal_title：Ophthalmology

authors： Cope JR,Collier SA,Schein OD,Brown AC,Verani JR,Gallen R,Beach MJ,Yoder JS

更新日期：2016-07-01 00:00:00

abstract：:Retinal detachment is an important cause of visual loss. Currently, surgical techniques, including vitrectomy, scleral buckle, and pneumatic retinopexy, are the only means to repair retinal detachment and restore vision. However, surgical failure rates may be as high as 20%, and visual outcomes continue to vary second...

journal_title：Ophthalmology

authors： Wubben TJ,Besirli CG,Zacks DN

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:To investigate if previous intravitreal therapy is a predictor of posterior capsule rupture (PCR) during cataract surgery. DESIGN:Multicenter, national electronic medical record (EMR) database study with univariate and multivariate regression modeling. PARTICIPANTS:A total of 65 836 eyes of 44 635 patients un...

journal_title：Ophthalmology

authors： Lee AY,Day AC,Egan C,Bailey C,Johnston RL,Tsaloumas MD,Denniston AK,Tufail A,United Kingdom Age-related Macular Degeneration and Diabetic Retinopathy Electronic Medical Records Users Group.

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To determine the heritability of nuclear cataract progression and to explore prospectively the effect of dietary micronutrients on the progression of nuclear cataract. DESIGN:Prospective cohort study. PARTICIPANTS:Cross-sectional nuclear cataract and dietary measurements were available for 2054 white female t...

journal_title：Ophthalmology

authors： Yonova-Doing E,Forkin ZA,Hysi PG,Williams KM,Spector TD,Gilbert CE,Hammond CJ

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To compare diabetic retinopathy (DR) identification and ungradable image rates between nonmydriatic ultrawide field (UWF) imaging and nonmydriatic multifield fundus photography (NMFP) in a large multistate population-based DR teleophthalmology program. DESIGN:Multiple-site, nonrandomized, consecutive, cross-se...

journal_title：Ophthalmology

authors： Silva PS,Horton MB,Clary D,Lewis DG,Sun JK,Cavallerano JD,Aiello LP

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To assess the prevalence of subretinal drusenoid deposits (SDD) in older adults with healthy maculas and early and intermediate age-related macular degeneration (AMD) using multimodal imaging. DESIGN:Cross-sectional study. PARTICIPANTS:A total of 651 subjects aged ≥60 years enrolled in the Alabama Study of Ea...

journal_title：Ophthalmology

authors： Zarubina AV,Neely DC,Clark ME,Huisingh CE,Samuels BC,Zhang Y,McGwin G Jr,Owsley C,Curcio CA

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To investigate the prevalence, features, associated factors, and reproducibility of segmentation errors in macular ganglion cell inner plexiform layer (GCIPL) thickness measurement as determined by optical coherence tomography (OCT). DESIGN:Cross-sectional study. PARTICIPANTS:Five hundred thirty-eight glaucom...

journal_title：Ophthalmology

authors： Hwang YH,Kim MK,Kim DW

更新日期：2016-05-01 00:00:00

abstract：TOPIC:Macular parameters have been proposed as an alternative to retinal nerve fiber layer (RNFL) parameters to diagnose glaucoma. Comparing the diagnostic accuracy of macular parameters, specifically the ganglion cell complex (GCC) and ganglion cell inner plexiform layer (GCIPL), with the accuracy of RNFL parameters f...

journal_title：Ophthalmology

authors： Oddone F,Lucenteforte E,Michelessi M,Rizzo S,Donati S,Parravano M,Virgili G

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To identify safety and effectiveness outcomes of office-based cataract surgery. Each year, approximately 3.7 million cataract surgeries in the United States are performed in Ambulatory Surgery Center (ASC) and Hospital Outpatient Department (HOPD) locations. Medicare in July 2015 published a solicitation for ex...

journal_title：Ophthalmology

authors： Ianchulev T,Litoff D,Ellinger D,Stiverson K,Packer M

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:To assess changes in retinal nonperfusion (RNP) in patients with retinal vein occlusion (RVO) treated with ranibizumab. DESIGN:Secondary outcome measure in randomized double-masked controlled clinical trial. PARTICIPANTS:Thirty-nine patients with central RVO (CRVO) and 42 with branch RVO (BRVO). METHODS:Subj...

journal_title：Ophthalmology

authors： Mir TA,Kherani S,Hafiz G,Scott AW,Zimmer-Galler I,Wenick AS,Solomon S,Han I,Poon D,He L,Shah SM,Brady CJ,Meyerle C,Sodhi A,Linz MO,Sophie R,Campochiaro PA

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To describe the natural history of dry eye disease (DED), which chronically affects millions of people in the United States. DESIGN:This study is based on the Women's Health Study and Physicians' Health Studies, and uses questionnaires and medical records. PARTICIPANTS:A total of 398 men and 386 women who rep...

journal_title：Ophthalmology

authors： Lienert JP,Tarko L,Uchino M,Christen WG,Schaumberg DA

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:To define the incidence of pseudophakic macular edema (PME) after cataract surgery and to identify contributory risk factors. DESIGN:Retrospective database study of electronic medical records (EMRs). PARTICIPANTS:A total of 81984 eyes undergoing cataract surgery between December 2010 and December 2014 from 8 ...

journal_title：Ophthalmology

authors： Chu CJ,Johnston RL,Buscombe C,Sallam AB,Mohamed Q,Yang YC,United Kingdom Pseudophakic Macular Edema Study Group.

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:To evaluate the association between use of antiplatelet or anticoagulant drugs and retinal or subretinal hemorrhage in participants with neovascular age-related macular degeneration (AMD) in the Comparison of AMD Treatments Trials (CATT). DESIGN:Cohort study within CATT. PARTICIPANTS:Participants in CATT with...

journal_title：Ophthalmology

authors： Ying GS,Maguire MG,Daniel E,Grunwald JE,Ahmed O,Martin DF,Comparison of Age-Related Macular Degeneration Treatments Trials Research Group.

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:To determine 5-year outcomes of Descemet stripping endothelial keratoplasty (DSEK) for Fuchs' endothelial corneal dystrophy (FECD). DESIGN:Prospective cohort study. PARTICIPANTS:Fifty-two eyes of 45 subjects with FECD undergoing primary DSEK. METHODS:Subjects were examined before and at fixed intervals throu...

journal_title：Ophthalmology

authors： Wacker K,Baratz KH,Maguire LJ,McLaren JW,Patel SV

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To determine whether migraine is associated with an increased risk of developing ocular motor cranial nerve palsies (OMCNP). DESIGN:Nationwide retrospective cohort study. PARTICIPANTS:Medical records of patients with migraine who were entered in the National Health Insurance Research Database (NHIRD) between ...

journal_title：Ophthalmology

authors： Yang CP,Chen YT,Fuh JL,Wang SJ

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To measure the magnitude and direction of visual field (VF) rates of change in glaucoma patients after intraocular pressure (IOP) reduction with trabeculectomy. DESIGN:Retrospective, comparative, longitudinal cohort study. PARTICIPANTS:Patients with open-angle glaucoma. METHODS:Patients who underwent trabecu...

journal_title：Ophthalmology

authors： Caprioli J,de Leon JM,Azarbod P,Chen A,Morales E,Nouri-Mahdavi K,Coleman A,Yu F,Afifi A

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:PRIMARY OPEN-ANGLE GLAUCOMA SUSPECT PREFERRED PRACTICE PATTERN® GUIDELINES:Evidence-based update of the Primary Open-Angle Suspect Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary open-angle glaucoma suspect with detailed recommendations...

journal_title：Ophthalmology

authors： Prum BE Jr,Lim MC,Mansberger SL,Stein JD,Moroi SE,Gedde SJ,Herndon LW Jr,Rosenberg LF,Williams RD

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To determine the proportion of solid organ transplant recipients developing periocular nonmelanoma skin cancer and to describe the morbidity of these cancers in transplant recipients. DESIGN:Cohort study. PARTICIPANTS:Consecutive patients undergoing solid organ transplantation at the Cleveland Clinic between ...

journal_title：Ophthalmology

authors： Perry JD,Polito SC,Chundury RV,Singh AD,Fritz MA,Vidimos AT,Gastman BR,Koyfman SA

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To assess the visual outcomes of cataract surgery in eyes that received fluocinolone acetonide implant or systemic therapy with oral corticosteroids and immunosuppression during the Multicenter Uveitis Steroid Treatment (MUST) Trial. DESIGN:Nested prospective cohort study of patients enrolled in a randomized c...

journal_title：Ophthalmology

authors： Sen HN,Abreu FM,Louis TA,Sugar EA,Altaweel MM,Elner SG,Holbrook JT,Jabs DA,Kim RY,Kempen JH,Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study Research Group.

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Lifitegrast is an integrin antagonist that decreases T-cell-mediated inflammation associated with dry eye disease (DED). We report the results of OPUS-2, a phase III study evaluating the efficacy and safety of lifitegrast compared with placebo for the treatment of DED. DESIGN:A 12-week, multicenter, randomized...

journal_title：Ophthalmology

authors： Tauber J,Karpecki P,Latkany R,Luchs J,Martel J,Sall K,Raychaudhuri A,Smith V,Semba CP,OPUS-2 Investigators.

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To analyze visual acuity (VA) outcomes before and after preplanned treatment regimen change in the VIEW studies at week 52 (W52). DESIGN:Multiple post hoc analyses for retrospectively defined subgroups in 2 multicenter, multinational, double-masked trials. PARTICIPANTS:Two thousand four hundred fifty-seven ne...

journal_title：Ophthalmology

authors： Richard G,Monés J,Wolf S,Korobelnik JF,Guymer R,Goldstein M,Norenberg C,Sandbrink R,Zeitz O

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:The Argus I implant is the first-generation epiretinal prosthesis approved for an investigational clinical trial by the United States Food and Drug Administration. Herein we report testing results obtained from a 10-year follow-up to study the physiologic effects of the bioelectronic visual implant after prolon...

journal_title：Ophthalmology

authors： Yue L,Falabella P,Christopher P,Wuyyuru V,Dorn J,Schor P,Greenberg RJ,Weiland JD,Humayun MS

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To determine the accuracy of patient-physician communication regarding topical ophthalmic medication use based on bottle cap color, particularly among individuals who may have acquired color vision deficiency from glaucoma. DESIGN:Cross-sectional, clinical study. PARTICIPANTS:Patients aged ≥18 years with prim...

journal_title：Ophthalmology

authors： Dave P,Villarreal G Jr,Friedman DS,Kahook MY,Ramulu PY

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:A MATLAB-based (The MathWorks, Inc, Natick, MA) computer program (the ganglion cell-inner plexiform layer [GCIPL] hemifield test) for automated detection of GCIPL thickness difference across the horizontal raphe was developed, and its glaucoma diagnostic performance was assessed. DESIGN:Cross-sectional study. ...

journal_title：Ophthalmology

authors： Kim YK,Yoo BW,Kim HC,Park KH

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:We compared smartphone fundus photography, nonmydriatic fundus photography, and 7-field mydriatic fundus photography for their abilities to detect and grade diabetic retinopathy (DR). DESIGN:This was a prospective, comparative study of 3 photography modalities. PARTICIPANTS:Diabetic patients (n = 300) were re...

journal_title：Ophthalmology

authors： Ryan ME,Rajalakshmi R,Prathiba V,Anjana RM,Ranjani H,Narayan KM,Olsen TW,Mohan V,Ward LA,Lynn MJ,Hendrick AM

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To assess the character and cause of photopsias in vitreoretinal patients. DESIGN:Cross-sectional study. PARTICIPANTS:A total of 169 consecutive patients (217 eyes) with vitreoretinal disease presenting with a history of photopsias. METHODS:A total of 217 eyes with photopsias in 169 patients were evaluated. ...

journal_title：Ophthalmology

authors： Brown GC,Brown MM,Fischer DH

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To examine the prevalence of fundus tessellation and its associated factors. DESIGN:Population-based study. PARTICIPANTS:The Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6±9.8 years (range, 50-93 years). METHODS:Participants underwent a comprehensive ophthalmic examination. By using...

journal_title：Ophthalmology

authors： Yan YN,Wang YX,Xu L,Xu J,Wei WB,Jonas JB

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To compare clinical outcomes using 20% sulfur hexafluoride (SF6) versus 100% air as a tamponade for graft attachment in Descemet membrane endothelial keratoplasty (DMEK). DESIGN:Retrospective, comparative, interventional case series. PARTICIPANTS:Pseudophakic patients with Fuchs' endothelial dystrophy or pseu...

journal_title：Ophthalmology

authors： Güell JL,Morral M,Gris O,Elies D,Manero F

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To analyze the clinical characteristics of a serous retinopathy associated with mitogen-activated protein kinase kinase (MEK) inhibition with binimetinib treatment for metastatic cutaneous melanoma (CM) and uveal melanoma (UM), and to determine possible pathogenetic mechanisms that may lead to this retinopathy....

journal_title：Ophthalmology

authors： van Dijk EH,van Herpen CM,Marinkovic M,Haanen JB,Amundson D,Luyten GP,Jager MJ,Kapiteijn EH,Keunen JE,Adamus G,Boon CJ

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To calculate the relationship between Medicare payment and service volume for the 3 highest-volume retina procedures: intravitreal injection (Current Procedural Terminology [CPT] code 67028), laser treatment for retinal edema (CPT code 67210), and laser treatment for proliferative retinopathy (CPT code 67228). ...

journal_title：Ophthalmology

authors： Gong D,Jun L,Tsai JC

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To investigate the association of reticular pseudodrusen (RPD) with Sorsby fundus dystrophy (SFD). DESIGN:Prospective, monocenter, cross-sectional case series. SUBJECTS:Sixteen patients of 4 unrelated families with SFD caused by mutations in TIMP3. METHODS:All subjects underwent multimodal imaging including ...

journal_title：Ophthalmology

authors： Gliem M,Müller PL,Mangold E,Bolz HJ,Stöhr H,Weber BH,Holz FG,Charbel Issa P

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Patients undergoing enucleation for uveal melanoma need to be informed of the possibility of phantom eye syndrome (PES). The number with uveal melanoma in PES studies has been small. Aims were to: (1) determine the prevalence, symptoms, and characteristics of PES and to test associations of PES symptoms with so...

journal_title：Ophthalmology

authors： Hope-Stone L,Brown SL,Heimann H,Damato B,Salmon P

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To review the published literature on safety and outcomes of the Boston type I keratoprosthesis (BI-KPro) for the surgical treatment of corneal opacification not amenable to human cadaveric corneal transplantation. METHODS:Searches of peer-reviewed literature were conducted in PubMed and the Cochrane Library...

journal_title：Ophthalmology

authors： Lee WB,Shtein RM,Kaufman SC,Deng SX,Rosenblatt MI

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare patient-reported symptoms of dry eye disease (DED) as assessed by the Ocular Surface Disease Index (OSDI), a 12-item symptom frequency-based questionnaire, and the Symptom Assessment iN Dry Eye (SANDE), a 2-item frequency- and severity-based visual analog scale. DESIGN:Clin...

journal_title：Ophthalmology

authors： Amparo F,Schaumberg DA,Dana R

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:To determine whether scatter and grid laser photocoagulation (laser) adds benefit to ranibizumab injections in patients with macular edema from retinal vein occlusion (RVO) and to compare 0.5-mg with 2.0-mg ranibizumab. DESIGN:Randomized, double-masked, controlled clinical trial. PARTICIPANTS:Thirty-nine pati...

journal_title：Ophthalmology

authors： Campochiaro PA,Hafiz G,Mir TA,Scott AW,Solomon S,Zimmer-Galler I,Sodhi A,Duh E,Ying H,Wenick A,Shah SM,Do DV,Nguyen QD,Kherani S,Sophie R

更新日期：2015-07-01 00:00:00